Average Ratings 0 Ratings
Average Ratings 0 Ratings
Description
Aurora utilizes principles of quantum mechanics and thermodynamics alongside a sophisticated continuous water model to assess the solvation effects on ligand binding affinities. This methodology is significantly different from the traditional scoring functions typically employed for predicting binding affinities. By integrating entropy and aqueous electrostatic contributions directly into the computations, Aurora's algorithms yield far more precise and reliable binding free energy values. The interaction between a ligand and a protein is fundamentally defined by the binding free energy value. This free energy (F) serves as a thermodynamic measure that correlates directly with the experimentally determined inhibition constant (IC50), influenced by factors such as electrostatic interactions, quantum effects, aqueous solvation forces, and the statistical characteristics of the molecules involved. Non-additivity in F arises primarily from two key components: the electrostatic and solvation energy, and the entropy, which together contribute to the complexity of ligand-protein interactions. Understanding these contributions is essential for the accurate prediction of binding affinities in drug design and molecular biology.
Description
FAID Quantum is an advanced software designed to assess fatigue levels and assist organizations in managing work hours as part of their fatigue management strategies. Drawing from real-world data, this tool has been effectively implemented in various sectors such as rail, aviation, mining, law enforcement, emergency services, healthcare, construction, and energy, among others. It aligns with ICAO standards and facilitates proactive, reactive, and predictive approaches to fatigue management. By employing two validated biomathematical models, FAID Quantum enhances the understanding of fatigue exposure significantly. The software is not only practical and proven but also offers a cost-effective solution for managing fatigue. It boasts highly precise predictions of sleep-wake patterns and allows users to establish fatigue tolerance thresholds alongside task risk assessments. Additionally, features such as optional calculations for time zone changes and circadian disruptions, as well as crew augmentation capabilities for long-haul flights, further enhance its utility. This comprehensive approach ensures that organizations can effectively maintain safety and productivity in their operations.
API Access
Has API
API Access
Has API
Integrations
No details available.
Integrations
No details available.
Pricing Details
No price information available.
Free Trial
Free Version
Pricing Details
No price information available.
Free Trial
Free Version
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Vendor Details
Company Name
Aurora Fine Chemicals
Founded
1990
Country
United States
Website
aurorafinechemicals.com/drug-discovery-software.html
Vendor Details
Company Name
InterDynamics
Founded
1992
Country
Australia
Website
www.interdynamics.com/fatigue-risk-management-solutions/fatigue-risk-management-products/faid-quantum-software/